Benefits of Inositol for PCOS
A healthy diet and lifestyle play important roles in managing PCOS. As a registered dietitian, I always take a “food first” approach. But the good news is that certain supplements can also play a role in managing PCOS naturally. Inositol is a supplement I recommend to the majority of my patients. Read on to learn about the benefits of inositol for PCOS.
*Updated 10.22
What is inositol?
Inositol is a B-vitamin-like nutrient and naturally occurring sugar that’s made by the human body and is also found in whole grains, beans, nuts, and fruits. In addition, it’s available as a dietary supplement.
There are nine types of inositol occurring in nature. Two forms, myo-inositol (myo) and D-chiro-inositol (DCI), have specific functions in our cells. Many recent studies have shown that a certain ratio of these two forms seems to work better than either form alone. That ratio is 40 to 1, meaning forty parts myo-inositol to one part D-chiro-inositol.
How does inositol work?
Inositol is used in the body a few different ways, including:
1. Builds cell membranes.
2. Acts as a “secondary messenger” in the central nervous system, which is one reason it’s known to increase the impact of neurotransmitters in your brain.
3. Acts as a messenger to help your body use insulin.
Number 3 is very important for women with PCOS as it plays a role in decreasing insulin resistance (IR)Here is a quick refresher of insulin resistance:
When you eat (especially carbs), your body breaks the food down into glucose in your bloodstream. You then secrete a hormone called insulin to get the sugar out of the blood and into the cells to be used for energy. In order for this to happen, insulin has to bind to a receptor on the surface of the cell to get the cell door to open. I like to explain it as “a key (insulin) unlocking the door (the cell).” When insulin binds to its receptor, it “unlocks” and releases secondary messengers. These secondary messengers tell the cell it’s time to take in glucose from the blood. Inositols function as secondary messengers. This means that inositols help with insulin signaling. In other words, they help the cell take in glucose from the blood.
It’s believed that women with PCOS who are insulin resistant do not properly release secondary messengers (like inositol). Glucose does not get into the cell efficiently. Therefore, glucose in the blood remains high, which tells the pancreas to make more insulin. The over-production of insulin results in both high insulin levels and high blood sugar. And as we know too well, these high levels of insulin cause many of the symptoms of PCOS.
Insulin resistance is also found in gestational diabetes, metabolic syndrome, and type 2 diabetes.
Benefits of inositol for PCOS
Inositol supplements have been found to have numerous health benefits for women with PCOS. Published studies confirm that inositol supplementation can improve insulin sensitivity, reduce serum levels of insulin, testosterone, and LH, and induce ovulation in women with PCOS. Some of these studies are using myo-inositol, others d-chiro and still others have the combination of myo:DCI. Read the references below to get details on the studies.
-
Insulin Resistance
Decreased insulin levels: Numerous studies show myo- inositol decreases insulin levels.
- Regulate menstrual cycles and improves ovulation. Researchers found that myo and DCI were able to enhance oocyte (ovarian cells) follicular development and maturation—which can support ovulation and regular cycles. Other studies have shown that ovarian function overall increases in women supplementing with inositol
- Improved egg quality. It’s recommended you use a combo of myo and D chiro for egg quality. A recent study showing that the oocyte quality and ovarian response have been progressively worsened by the increased dosage of DCI alone. Therefore, DCI supplementation alone is not recommendable for several reasons: (a) high doses of DCI/day have been considered toxic to ovaries and oocyte maturation; (b) DCI is not converted into MI; therefore, the specific action exerted by the last one would be lost; (c) MI and MI-IPG deficiencies are correlated with many IR conditions. Reference
- Improved metabolic issues like inflammation and hypertension
- Since inositol may decrease insulin levels, it can also help with reducing hirsutism and decreasing acne. You may need 24 weeks of supplementation until you notice a difference in both acne and hirsutism.
- Improved lipids
- Decreased anxiety. It works by activating serotonin receptors, which may improve depression and anxiety.
- Possible effect of wt loss. The evidence here is not as strong, but some studies suggest it may have an effect.
- Decreased carb cravings. This one is more anecdotal! But many of my patients report reduced carb cravings when taking inositol.
What is the recommended dose?
The recommended dose of myo-inositol for most people is 2,000 mg, and the recommended dose of D-chiro-inositol is 50 mg, taken twice a day (total daily dose of 4,000 mg of myo-inositol plus 100 mg of D-chiro-inositol). It takes at least three months of consistent use to see inositol benefits.
Why I recommend Ovasitol brand
Ovasitol is an inositol supplement scientifically formulated to promote menstrual regularity and normal ovarian function. Manufactured by THERALOGIX, it is the first and only inositol supplement that has been independently verified for content accuracy, purity, and freedom from contaminants through a not-for-profit certification program (NSF® International). Ovasitol is formulated by an advisory board of leading reproductive health specialists.
Ovasitol is the only supplement in the United States to contain a combination of myo-inositol and D-chiro-inositol, in the body’s natural ratio of 40 to 1. Recent studies have shown that taking a combination of these two forms, in this ratio, is more beneficial to women with PCOS than taking MYO or DCI alone. Better yet: Ovasitol is also much more affordable than other popular inositol supplements for PCOS.
The dose for Ovasitol is 2 packets a day. It comes in a powder form and you can take it with or without food. It can also be mixed into a liquid.
You can also look for your another brand, however I recommend looking for one that is NSF certified. This means the supplement has been independently verified for content accuracy and purity.
Are there any side effects of Ovasitol?
As per the Ovasitol website: There are no expected side effects from Ovasitol. Studies have shown that inositol is safe and well-tolerated when taken at the typical recommended dose of 4,000 mg a day. Ovasitol can be taken along with most other nutritional supplements and prescription medications, including metformin. Ovasitol is safe to continue throughout pregnancy. As with any dietary supplement, it is important to discuss the use of all medications, vitamins and supplements with your healthcare team.
*If you choose to purchase myo and d-chiro separately, do not take d-chiro by itself without myo as it can worsen egg quality if you are trying to conceive. Your best bet would be to add myo as well.
NOTE: if you want to purchase Ovasitol, use my code 110202 to get a discount.
Disclaimer: it is always recommended that you check with your physician before taking any supplement
Are you taking insitol – or Ovasitol? I’d love to hear if it’s made a difference in your symptoms!
References:
Inositol references. This pdf contains numerous studies on inositol.
Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials
Debates Regarding Lean Patients with Polycystic Ovary Syndrome: A Narrative Review
RELATED POSTS
MEET MARTHA
I especially love problem-solving, whether it’s helping women defeat issues plaguing them for years, helping a busy executive find practical ways to get heart healthy, or providing tips to help you reverse diabetes. That’s why I’m on a constant quest to expand my knowledge by staying on top of the latest research.
14 Comments
Leave a Comment
20 Ways To Eat Out 550 Calories or Less!
No time to cook? We’ve got you covered. Here are 20 healthy meals from a variety of cuisines that won’t pack on the pounds. Most of them also have less than 30 grams of carbs.
Subscribe to my newsletter and get this free download.
I’m 53 and in menopause. I have PCOS. My two biggest struggles are weight loss and now mail pattern balding. I do not have diabetes, but am currently waiting test results for insulin resistance. Would Ovasotil be good for me to help with those issues.
sorry for my late reply – but the answer is yes!
Getting Back Stolen, Lost, Or Hacked Crypto /Hack Wizard Recovery cyber services.
Although recovering stolen cryptocurrency can be difficult, experts like Hack Wizard Recovery cyber services
can assist you in getting your lost Bitcoin back. Captain Hack Wizard Recovery cyber services begins the cryptocurrency scam recovery process by looking into the story of events and the scheme’s timetable in order to guarantee a successful outcome for the recovery of lost assets. He then tracks down your virtual assets and examines the data that is at his disposal. Consult Hack Wizard Recovery cyber services. If you want to get your misplaced Bitcoin back. get in touch with Hack Wizard Recovery cyber services at
EMAIL:HackWizardRecoverycyberservices@proton.me
WHATSAPP:+12623256979.
Yes – inositol can be beneficial even for women going through menopause – assuming you have some issues with insulin resistance.
Getting Back Stolen, Lost, Or Hacked Crypto /Hack Wizard Recovery cyber services.
Although recovering stolen cryptocurrency can be difficult, experts like Hack Wizard Recovery cyber services
can assist you in getting your lost Bitcoin back. Captain Hack Wizard Recovery cyber services begins the cryptocurrency scam recovery process by looking into the story of events and the scheme’s timetable in order to guarantee a successful outcome for the recovery of lost assets. He then tracks down your virtual assets and examines the data that is at his disposal. Consult Hack Wizard Recovery cyber services. If you want to get your misplaced Bitcoin back. get in touch with Hack Wizard Recovery cyber services at
EMAIL:HackWizardRecoverycyberservices@proton.me
WHATSAPP:+12623256979.
It’s made my pcos acne worse. I was so hoping this would work but it’s made it worse. I took pure encapsulations Inositol which is myo only. Maybe I took the wrong one?
The theralogix one is amazing. It helped with carb cravings which in turn can lead to weight loss cause you aren’t overeating. It helped with acne. You need one with myo and dci. The combination really seems to be a winner.
Getting Back Stolen, Lost, Or Hacked Crypto /Hack Wizard Recovery cyber services.
Although recovering stolen cryptocurrency can be difficult, experts like Hack Wizard Recovery cyber services
can assist you in getting your lost Bitcoin back. Captain Hack Wizard Recovery cyber services begins the cryptocurrency scam recovery process by looking into the story of events and the scheme’s timetable in order to guarantee a successful outcome for the recovery of lost assets. He then tracks down your virtual assets and examines the data that is at his disposal. Consult Hack Wizard Recovery cyber services. If you want to get your misplaced Bitcoin back. get in touch with Hack Wizard Recovery cyber services at
EMAIL:HackWizardRecoverycyberservices@proton.me
WHATSAPP:+12623256979.
Thank you – I’m not overweight though. I am a skinny PCOSer.
So frustrating that inositol seems to work for 99% of the PCOS population but for a few of is it doesn’t – of you google inositol made my acne worse you will see several threads.
Getting Back Stolen, Lost, Or Hacked Crypto /Hack Wizard Recovery cyber services.
Although recovering stolen cryptocurrency can be difficult, experts like Hack Wizard Recovery cyber services
can assist you in getting your lost Bitcoin back. Captain Hack Wizard Recovery cyber services begins the cryptocurrency scam recovery process by looking into the story of events and the scheme’s timetable in order to guarantee a successful outcome for the recovery of lost assets. He then tracks down your virtual assets and examines the data that is at his disposal. Consult Hack Wizard Recovery cyber services. If you want to get your misplaced Bitcoin back. get in touch with Hack Wizard Recovery cyber services at
EMAIL:HackWizardRecoverycyberservices@proton.me
WHATSAPP:+12623256979.
My husband left me for another woman a few months ago and ever since then my life has been filled with pain and agony because my husband was my first love whom I have spent my entire life with. A friend and also a colleague from work told me he saw some testimonies of a spiritual counselor called Doctor Muna, He can bring back lover within some few days. Ridiculously, I laughed it out and said I am not interested. But for friendship’s sake, she consulted this God sent man on my behalf and to my greatest surprise, Immediately after 12 hours, my husband called me for the very first time for over 7 months saying “I miss you babe and I’m so sorry for everything I made you went through” I couldn’t say a word but cried over the phone and hanged up. We are back together and living Happily together again. To be honest, I still can’t believe it, because it’s highly unbelievable. Thank you DOCTOR MUNA for bringing back my love and also to my SELFLESS FRIEND. Laura, who interceded on my behalf. For anyone who might need help of this wonderful spiritual counselor, here is the email address: marvelspelltemple@gmail.com, Also add him on WhatsApp: +2347035449257
I recently went through a tough breakup. My 5 years relationship ended a month ago, and it’s been really hard for me. I still love my ex-girlfriend so much and can’t stop thinking about her. I’ve tried everything to win her back, but nothing has worked. It’s frustrating, and I can’t imagine being with anyone else. I’ve been trying to move on, but I can’t seem to get her out of my mind. I know it might sound strange to share this here. Until a spiritual counselor became my only hope and confidence to her back into my life again. marvelspelltemple@gmail.com reunited us again
Am so excited to share my testimony of a real spell caster who brought my husband back to me. My husband and I have been married for about 6yrs now. We were happily married with two kids, 3 months ago, I started to notice some strange behavior from him and a few weeks later I found out that my husband is seeing someone else. I became very worried and I needed help. I did all I could to save my marriage but it fail until a friend of mine told me about the wonderful work of Dr Jakuta I contacted him and he assured me that after 24hrs everything will return back to normal, to my greatest surprise my husband came back home and went on his knees was crying begging me for forgiveness I’m so happy right now. Thank you so much Dr Jakuta because ever since then everything has returned back to normal. One message to him today can change your life too for the better. You can contact him via WhatsApp +2349161779461 or Email : doctorjakutaspellcaster24@gmail.com
I am out here to speed this good news to the entire world on how I got help from Dr UYI a great lottery spell caster that will help you cast a lottery spell and give you the rightful numbers to win the lottery, I didn’t believe lottery spell at first but as life got harder i decided to give a try, I spend so much money on tickets just to make sure I win. until the day I met Dr UYI online, which so many people have talked good about, that he is very great when it comes to casting lottery spell, he told me the necessary things to do and behold it was like a magic, i won $220 Million Dollars Mega Million with the numbers Dr UYI gave to me. his a really trustful person worthy and reliable, i am sharing this to you who have been finding it so hard to win the lottery, Thanks you Dr UYI who helped me Contact him via email: drzukalottospelltemple@gmail.com OR WhatsApp on +17174154115